1981 – Studie ~ The cannabinoids as potential antiepileptics.

1982 – Studie ~ Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice.

2000 – Studie ~ Neuroprotective Antioxidants from Marijuana.

2000 – Studie ~ Different effects of nabilone and cannabidiol on binocular depth inversion in Man.

2000 – Studie ~ Synthesis of a primary metabolite of cannabidiol.

2000 – Studie ~ Cannabinoids in clinical practice.

2000 – News ~ Marijuana Extract Helps Arthritis Pain.

2001 – Studie ~ Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters.

2005 – Studie – Cannabidiol lowers incidence of diabetes in non-obese diabetic mice.

2005 – Studie – Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.

2005 – Studie –  Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia.

2005 – Studie ~ Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism.

2005 – Studie ~ Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1A Receptor–Dependent Mechanism.

2005 – Studie ~ Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival.

2005 – Studie ~ Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors.

2005 – Studie ~ Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.

2005 – Studie ~ Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson’s disease.

2005 – News ~ Chemicals in Cannabis may help mentally ill.

2006 – Studie – Cannabidiol-Induced Apoptosis in Human Leukemia Cells.

2006 – Studie – The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells.

2006 – Studie – Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes.

2006 – Studie – The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.

 Cannabidiol has a cerebroprotective action.

2006 – Studie – Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug.

2006 – Studie ~ Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes.

2006 – Studie ~ A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol.

2006 – Studie ~ The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells.

2006 – Studie ~ Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats.

2006 – Studie ~ Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test.

2006 – Studie ~ Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia.

2006 – Studie ~ The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells.

2006 – Studie ~ Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement.

2006 – News ~ Compound found in marijuana may defend against diabetic retinopathy.

2006 – News – Cannabidiol inhibits tumour growth in leukaemia and breast cancer.

2007 – Studie – The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin.

2007 – Studie – Cannabidiol and (delta)9-tetrahydrocannabinol are neuroprotective antioxidants.

2007 – Studie – Cannabidiol in vivo blunts B-amyloid induced neuroinflammation by suppressing IL-1B and iNOS expression.

2007 – Studie – Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption.

2007 – Studie ~ Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.

2007 – Studie ~ The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.

2007 – Studie ~ Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury.

2007 – Studie ~ Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro.

2007 – Studie ~ Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism.

2007 – Studie ~ Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells.

2007 – Studie ~ The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids.

2007 – Studie ~ US Patent Application 20070099987 – Treating or preventing diabetes with cannabidiol.

2007 – Studie ~ Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance.

2007 – Studie ~ Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue.

2007 – Studie ~ Cannabidiol–recent advances.

2007 – News – Who’s Afraid of Cannabidiol?

2007 – News ~ Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease).

2007 – News ~ Marijuana Compound Shows Promise In Fighting Breast Cancer.

2007 – News ~ Cannabis may stop Breast Cancer from spreading in the Body.

2007 – News ~ Cannabis compound cannabidiol CBD ‘halts cancer.

2007 – News ~ Cannabis compound stops spread of breast cancer: researchers.

2008 – Studie – Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.

2008 – Studie – Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action.

2008 – Studie – Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of delta9-tetrahydrocannabinol.

2008 – Studie – The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent.

2008 – Studie – Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders.

2008 – Studie ~ US Patent Application 20080262099 – Inhibition of Tumour Cell Migration.

2008 – Studie ~ Mediation of Cannabidiol anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor.

2008 – Studie ~ Antibacterial cannabinoids from Cannabis sativa: a structure-activity Studie.

2008 – Studie ~ Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation.

2008 – Studie ~ Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis.

2008 – Studie ~ The role of the endocannabinoid system in Alzheimer’s disease: facts and hypotheses.

2008 – Studie ~ A comparative Studie on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cell.

2008 – Studie ~ 5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid.

2008 – Studie ~ Inhibition of Breast Cancer Aggressiveness by Cannabidiol.

2009 – Studie – Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.

2009 – Studie – Cannabidiol-2,6-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and Selective 15-Lipoxygenase Inhibitor.

2009 – Studie – Beneficial effects of a Cannabis sativa extract treatment on diabetes-induced neuropathy and oxidative stress.

2009 – Studie – Opposite Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.

2009 – Studie – Cannabidiol: a promising drug for neurodegenerative disorders.

2009 – Studie – Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis.

2009 – Studie – Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation.

2009 – Studie – Modulation of effective connectivity during emotional processing by Delta9-tetrahydrocannabinol and cannabidiol.

2009 – Studie ~ Therapeutic time window of cannabidiol treatment on delayed ischemic damage via high-mobility group box1-inhibiting mechanism.

2009 – Studie ~ Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells.

2009 – Studie ~ Non-psychotropic plant cannabinoids:new therapeutic opportunities from an
ancient herb.

2009 – Studie ~ Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation.

2009 – Studie ~ Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception.

2009 – Studie ~ The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.

2009 – Studie ~ Cannabinoids as novel anti-inflammatory drugs.

2009 – Studie ~ Cannabidiol, a Nonpsychotropic Component of Cannabis, Inhibits Cue-Induced Heroin Seeking and Normalizes Discrete Mesolimbic Neuronal Disturbances.

2009 – Studie ~ Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development.

2009 – Studie ~ Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death.

2009 – Studie ~ The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function.

2009 – Studie ~ Cannabidiol-induced lymphopenia does not involve NKT and NK cells.

2009 – Studie ~ Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania.

2009 – Studie ~ Cannabidiol Attenuates Myocardial Dysfunction, Fibrosis, Inflammation, Cell Death and Interrelated Signaling Pathways Associated With Diabetic Cardiomyopathy.

2009 – Studie ~ Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats.

2009 – Studie ~ Cannabidiol-2′,6′-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and Selective 15-Lipoxygenase Inhibitor.

2009 – Studie ~ Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats.

2009 – Studie ~ Opposite Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.

2009 – Studie ~ Time-dependent vascular actions of cannabidiol in the rat aorta.

2009 – Studie ~ Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels.

2009 – Studie ~ Cannabidiol for the treatment of psychosis in Parkinson’s disease.

2009 – Studie ~ Modulation of effective connectivity during emotional processing by Delta9-tetrahydrocannabinol and cannabidiol.

2009 – News – Cannabis by product helps reduce effects of Parkinson disease medication.

2009 – News ~ Cannabis compound can help cells.

2009 – News ~ Cannabis plant extracts could potentially form the basic ingredients for a market-leading diabetes drug.

2009 – News ~ Marijuana Chemicals Ease MS Symptoms, Review Confirms.

2010 – Studie – Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.

2010 – Studie – Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT receptors.

2010 – Studie – Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania.

2010 – Studie ~ Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain.

2010 – Studie ~ Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis.

2010 – Studie ~ Therapeutical use of the cannabinoids in psychiatry.

2010 – Studie ~ Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes.

2010 – Studie ~ Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke.

2010 – Studie ~ Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo.

2010 – Studie ~ Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.

2010 – Studie ~ Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.

2010 – Studie ~ Antitumorigenic Effects of Cannabinoids beyond Apoptosis.

2010 – Studie ~ Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy.

2010 – Studie ~ Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

2010 – Studie ~ Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation.

2010 – Studie ~ Anti-tumoural effects of cannabinoid combinations – Patent TW201002315 (A) ― 2010-01-16.

2010 – Studie ~ Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation.

2010 – Studie ~ A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice.

2010 – Studie ~ Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors.

2010 – Studie ~ Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic Studie.

2010 – Studie ~ Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells.

2010 – Studie ~ Regulation of nausea and vomiting by cannabinoids.

2010 – Studie ~ Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.

2010 – Studie ~ Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers.

2010 – Studie ~ Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic Studie.

2010 – Studie ~ Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.

2010 – Studie ~ Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival.

2010 – Studie ~ Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.

2010 – Studie ~ Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania.

2010 – Studie ~ Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis.

2010 – Studie ~ Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.

2010 – Studie ~ Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors.

2010 – Studie ~ Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity.

2010 – Studie ~ Multicenter, double-blind, randomized, placebo-controlled, parallel-group Studie of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.

2010 – Studie ~ Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry.

2010 – Studie ~ Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture.

2010 – Studie ~ Anticonvulsant effects of GWP42006 in vitro and in vivo in rat.

2010 – Studie ~ The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors.

2010 – Studie ~ Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report.

2010 – News ~ Non-psychoactive cannabis to be unveiled at Annual National Clinical Conference on Cannabis Therapeutics.

2010 – News ~ Prescription Marijuana Without “Intoxicating” Effect in Research Stage.

2010 – News ~ Key ingredient staves off marijuana memory loss.

2010 – News ~ Science: Cannabidiol enhances the anti-cancer effects of THC on human brain cancer cells.

2010 – News ~ Pot Compound Mitigates Diabetic Cardiomyopathy.

2010 – News ~ Cannabinoids inhibit and may prevent neuropathic pain in diabetes.

2010 – News ~ Lab Notes: Pot Has Benefits for Diabetic Hearts.

2010 – News ~ Cannabidiol (CBD) as an Anti-Arrhythmic – the Role of the CB1 Receptors.

2010 – News ~ Key ingredient dilutes marijuana’s effect on memory.

2010 – News – Brazilian Scientists Show How Marijuana Can Help in Treating Parkinson.

2011 – Studie ~ The potential for clinical use of cannabinoids in treatment of cardiovascular diseases.

2011 – Studie ~ Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.

2011 – Studie ~ Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy Studie.

2011 – Studie ~ Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement.

2011 – Studie ~ Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers’ disease.

2011 – Studie ~ Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa.

2011 – Studie ~ Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol.

2011 – Studie ~ Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis.

2011 – Studie ~ Cannabidiol, a Major Phytocannabinoid, as a Potent Atypical Inhibitor for Cytochrome P450 2D6.

2011 – Studie ~ Brief Report: Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice.

2011 – Studie ~ Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis.

2011 – Studie ~ Phytocannabinoids for use in the treatment of cancer – Patent GB2478595 (A) ― 2011-09-14.

2011 – Studie ~ US Patent Application 20110257256 – CANNABINOIDS FOR USE IN TREATING OR PREVENTING COGNITIVE IMPAIRMENT AND DEMENTIA.

2011 – Studie ~ Influence of agroclimatic conditions on content of main cannabinoids in industrial hemp (Cannabis sativa L.).

2011 – Studie ~ Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.

2011 – Studie ~ Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.

2011 – Studie ~ Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent.

2011 – Studie ~ Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors.

2011 – Studie ~ Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.

2011 – Studie ~ The Non-Psychoactive Plant Cannabinoid, Cannabidiol Affects Cholesterol Metabolism-Related Genes in Microglial Cells.

2011 – Studie ~ Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors.

2011 – Studie ~ Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice.

2011 – Studie ~ Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.

2011 – Studie ~ Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Studie.

2011 – Studie ~ CANNABIDIOL INHIBITS PATHOGENIC T-CELLS, DECREASES SPINAL MICROGLIAL ACTIVATION AND AMELIORATES MULTIPLE SCLEROSIS-LIKE DISEASE IN C57BL/6 MICE.

2011 – Studie ~ Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm.

2011 – Studie ~ Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders.

2011 – Studie ~ Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews.

2011 – Studie ~ Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus.

2011 – Studie ~ A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents.

2011 – Studie ~ Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists.

2011 – Studie ~ Cannabidiol potentiates Δ(9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.

2011 – Studie ~ Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility.

2011 – Studie ~ Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients.

2011 – Studie ~ Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats.

2011 – Studie ~ Cannabidiol induces programmed cell death in breast cancer cells by coordinating the crosstalk between apoptosis and autophagy.
2011 – Studie ~ Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.

2011 – Studie ~ Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats.

2011 – Studie ~ Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus.

2011 – Studie ~ Regulation of nausea and vomiting by cannabinoids.
2011 – Studie ~ The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus.

2011 – Studie ~ Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.

2011 – Studie ~ Cannabidiol Dampens Streptozotocin-Induced Retinal Inflammation by Targeting of Microglial Activation.

2011 – Studie ~ Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour.
2011 – Studie ~ Cannabis with high cannabidiol content is associated with fewer psychotic experiences.

2011 – Studie ~ A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents.

2011 – Studie ~ Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being.

2011 – Studie ~ Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report.
2011 – Studie ~ Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects.

2011 – Studie ~ The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives.

2011 – Studie ~ Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and cell death.

2011 – Studie ~ Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats.
2011 – Studie ~ Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.

2011 – Studie ~ Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia-ischemia in newborn pigs.

2011 – Studie ~ Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury.

2011 – Studie ~ Prospects for cannabinoid therapies in basal ganglia disorders.
2011 – Studie ~ Phytocannabinoids as novel therapeutic agents in CNS disorders.

2011 – Studie ~ Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9) -tetrahydrocannabinol in BV-2 microglial cells.

2011 – Studie ~ THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis.

2011 – Studie ~ Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration.

2011 – Studie ~ Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders.

2011 – Studie ~ The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects.

2011 – Studie ~ Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.

2011 – Studie ~ Heterogeneity in the composition of marijuana seized in California.

2011 – Studie ~ Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes.

2011 – Studie ~ Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.

2011 – Studie ~ A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells.

2011 – Studie ~ Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action.

2011 – Studie ~ Cannabidiol (CBD) as an Anti-Arrhythmic.

2011 – News ~ Cannabis could help treat epilepsy #1.

2011 – News ~ Cannabis could be used to treat epilepsy #2.

2011 – News ~ Marijuana Extract Might Help Prevent Chemotherapy-Related Nerve Pain.

2011 – News ~ Another Studie Confirms Anti-Cancer Effects of THC and CBD.

2011 – News ~ Cannabinoid ‘Completely’ Prevents Chemotherapy-Induced Neuropathy, Studie Says.

2011 – News ~ Cannabidiol May Fight Alzheimer’s Disease.

2011 – News ~ Marijuana Compound Induces Cell Death In Hard-To-Treat Brain Cancer.

2011 – News ~ Marijuana component may ease pain from chemo therapy drugs.

2011 – News ~ Pot Compound Exerts Anticonvulsant Effects In Animal Models Of Epilepsy.

2011 – News ~ New research provides hope for those with epilepsy.

2011 – News ~ Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis.

2011 – News ~ CBD Tops The Chart.

2012 – Studie ~ Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.

2012 – Studie ~ Topical and Systemic Cannabidiol Improves Trinitrobenzene Sulfonic Acid Colitis in Mice.

2012 – Studie ~ Islet protection and amelioration of diabetes type 2 in Psammomys obesus by treatment with cannabidiol.

2012 – Studie ~ Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.

2012 – Studie ~ Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: Role for the adenosine A(2A) receptor.

2012 – Studie ~ Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects.

2012 – Studie ~ The therapeutic potential of the endocannabinoid system for Alzheimer’s disease.

2012 – Studie ~ On Disruption of Fear Memory by Reconsolidation Blockade: Evidence from Cannabidiol Treatment.

2012 – Studie ~ Cannabinol and cannabidiol exert opposing effects on rat feeding patterns.

2012 – Studie ~ Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

2012 – Studie ~ CANNABIDIOL INHIBITS ANGIOGENESIS BY MULTIPLE MECHANISMS.

2012 – Studie ~ Non-THC cannabinoids counteract prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.

2012 – Studie ~ Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.

2012 – Studie ~ Poly-ε-caprolactone microspheres as a drug delivery system for cannabinoid administration: Development, characterization and in vitro evaluation of their antitumoral efficacy.

2012 – Studie ~ Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP(+) affected murine mesencephalic cultures.

2012 – Studie ~ Antipsychotic Profile of Cannabidiol and Rimonabant in an Animal Model of Emotional Context Processing in Schizophrenia.

2012 – Studie ~ Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia.

2012 – Studie ~ Cannabidiol-induced apoptosis in murine microglial cells through lipid raft.

2012 – Studie ~ Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report.

2012 – Studie ~ A critical review of the antipsychotic effects of Cannabidiol: 30 years of a translational investigation.

2012 – Studie ~ Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers.

2012 – Studie ~ Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.

2012 – Studie ~The potential use of cannabidiol in the therapy of metabolic syndrome.

2012 – Studie ~ Cannabinoid-like anti-inflammatory compounds from flax fiber.

2012 – Studie ~ Cannabidiol in Inflammatory Bowel Diseases: A Brief Overview.

2012 – News ~ Medical Marijuana: A “Cure” for Autism?

2012 – News ~ How marijuana could help cure obesity-related diseases.

2012 – News ~ Cannabis can help treat obesity.

2012 – News ~ Researchers Studie neuroprotective properties in cannabis.

2012 – Forum Post ~ Simple Method: Isolating & Extracting INDIVIDUAL Cannabinoids… from BadKittySmiles.